I'm not a local, but I've been many times.
Go to Ripley's Aquarium, and walk Broadway On The Beach. If you've never been to Hard Rock or Planet Hollywood go. It's neat to see those things. Captain George's buffet is a great place to eat! I don't eat seafood and still had plenty to eat. DH and his family eat seafood and they were in heaven! Nascar is fun for riding go-karts. There are TONS of Mini Golf places. We went to 3 in one night. It was fun.
If I think of anything else, I'll come back.
eta: Barefoot Landing has some neat shops and places too.
I was just there last week visiting my friend. I thankfully just missed bike week. She told me it gets really really crazy. There is tons of traffic everywhere! She also told me Ripley's acquarium isn't all that great. But Broadway at the Beach is definitely a must!